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Jeffery D Molkentin Selected Research

Peptidyl-Prolyl Isomerase F

4/2011Mechanisms of necroptosis in T cells.
4/2008Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy.

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Jeffery D Molkentin Research Topics

Disease

53Cardiomegaly (Heart Hypertrophy)
12/2018 - 03/2002
52Hypertrophy
10/2021 - 03/2002
42Heart Failure
01/2022 - 04/2002
29Fibrosis (Cirrhosis)
12/2018 - 04/2002
18Cardiomyopathies (Cardiomyopathy)
01/2019 - 02/2003
16Necrosis
05/2016 - 03/2005
15Myocardial Infarction
01/2018 - 01/2004
14Heart Diseases (Heart Disease)
11/2017 - 03/2002
14Muscular Dystrophies (Muscular Dystrophy)
05/2016 - 06/2006
12Ischemia
01/2020 - 01/2004
9Reperfusion Injury
01/2021 - 01/2004
9Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2017 - 03/2004
8Infarction (Infarctions)
04/2014 - 04/2004
6Body Weight (Weight, Body)
01/2021 - 04/2002
6Rupture
01/2020 - 08/2013
6Inflammation (Inflammations)
10/2017 - 04/2005
5Ventricular Remodeling
01/2018 - 08/2007
5Neoplasms (Cancer)
01/2012 - 07/2002
5Infections
03/2011 - 03/2002
4Sudden Death
01/2017 - 09/2003
4Pancreatitis
01/2016 - 04/2012
4Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy)
01/2011 - 06/2006
3Atrophy
01/2021 - 01/2010
3Cardiac Arrhythmias (Arrythmia)
01/2020 - 09/2003
3Cicatrix (Scar)
01/2018 - 01/2016
3Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
05/2016 - 03/2007
3Thrombosis (Thrombus)
07/2010 - 02/2008
2Insulin Resistance
11/2020 - 02/2013
2Type 2 Diabetes Mellitus (MODY)
11/2020 - 02/2010
2Hyperglycemia
01/2020 - 02/2010
2Pulmonary Hypertension
12/2019 - 05/2003
2Fatigue
11/2018 - 04/2015

Drug/Important Bio-Agent (IBA)

52CalcineurinIBA
11/2015 - 03/2002
31Proteins (Proteins, Gene)FDA Link
01/2020 - 04/2002
18CalciumIBA
05/2016 - 03/2002
16Transcription Factors (Transcription Factor)IBA
01/2020 - 08/2002
12Mitochondrial Permeability Transition PoreIBA
01/2021 - 09/2007
12Protein Isoforms (Isoforms)IBA
01/2015 - 12/2002
11Cyclophilins (Cyclophilin)IBA
01/2021 - 03/2005
8Mitogen-Activated Protein KinasesIBA
11/2020 - 04/2004
8Phosphotransferases (Kinase)IBA
01/2020 - 11/2002
8Phosphoric Monoester Hydrolases (Phosphatases)IBA
12/2019 - 03/2002
8PeriostinIBA
01/2017 - 08/2007
7CytokinesIBA
10/2018 - 04/2005
7Sarcoglycans (beta Sarcoglycan)IBA
12/2014 - 06/2006
6CollagenIBA
01/2021 - 02/2009
6Angiotensin IIIBA
11/2020 - 11/2002
6DNA (Deoxyribonucleic Acid)IBA
12/2019 - 01/2004
6DystrophinIBA
05/2016 - 01/2007
6Protein Kinases (Protein Kinase)IBA
01/2015 - 08/2006
6Transforming Growth Factors (Transforming Growth Factor)IBA
12/2014 - 02/2011
6Isoproterenol (Isoprenaline)FDA LinkGeneric
01/2012 - 05/2003
6Cyclosporine (Ciclosporin)FDA LinkGeneric
02/2011 - 04/2002
6Phosphoprotein Phosphatases (Phosphatases, Protein)IBA
02/2009 - 01/2004
5Calmodulin (Calcium-Dependent Activator Protein)IBA
01/2020 - 05/2002
5Protein Kinase CIBA
01/2018 - 02/2007
5p38 Mitogen-Activated Protein KinasesIBA
08/2017 - 05/2003
5LuciferasesIBA
09/2015 - 05/2003
5Histone Deacetylases (Histone Deacetylase)IBA
04/2013 - 03/2006
4RNA (Ribonucleic Acid)IBA
10/2021 - 11/2017
4Messenger RNA (mRNA)IBA
01/2020 - 02/2006
4DesminIBA
10/2018 - 12/2010
4TamoxifenFDA LinkGeneric
01/2017 - 02/2005
4Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
01/2016 - 11/2002
4MyostatinIBA
01/2016 - 06/2006
4Adenosine Triphosphate (ATP)IBA
01/2016 - 03/2008
41- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
01/2016 - 02/2008
4Tacrolimus (Prograf)FDA LinkGeneric
09/2015 - 03/2002
4Calcineurin InhibitorsIBA
09/2015 - 03/2002
4Peptides (Polypeptides)IBA
10/2011 - 02/2006
4Phenylephrine (Neo-Synephrine)FDA LinkGeneric
07/2011 - 05/2003
4cysteine and glycine-rich protein 3IBA
08/2006 - 03/2004
3Complementary DNA (cDNA)IBA
01/2021 - 02/2003
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2020 - 03/2011
3IntegrinsIBA
01/2019 - 08/2010
3Transforming Growth Factor beta (TGF-beta)IBA
10/2018 - 02/2006
3Crystallins (Crystallin)IBA
10/2018 - 09/2014
3ruboxistaurinIBA
12/2017 - 07/2009
3Creatine Kinase (Creatine Phosphokinase)IBA
03/2016 - 03/2011
3ChemokinesIBA
01/2016 - 04/2005
3Pharmaceutical PreparationsIBA
01/2016 - 02/2009
3Adenosine Triphosphatases (ATPase)IBA
01/2015 - 04/2009
3G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
02/2013 - 11/2002
3Insulin (Novolin)FDA Link
01/2013 - 01/2004
3Serine (L-Serine)FDA Link
07/2011 - 10/2004
3salicylhydroxamic acid (SHAM)IBA
02/2011 - 08/2007
3transcription factor NF-AT c3IBA
10/2008 - 06/2003
2Dual-Specificity PhosphatasesIBA
11/2020 - 04/2004
2Glucose (Dextrose)FDA LinkGeneric
11/2020 - 02/2011
2Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
01/2020 - 03/2006
2Transforming Growth Factor-beta Type II ReceptorIBA
12/2018 - 10/2018
2Carrier Proteins (Binding Protein)IBA
12/2018 - 01/2016
2Extracellular Matrix ProteinsIBA
01/2018 - 01/2009
2Glycoproteins (Glycoprotein)IBA
01/2018 - 03/2016
2Fibronectins (Fibronectin)IBA
01/2018 - 01/2012
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
08/2017 - 10/2014
2Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
01/2016 - 06/2011
2Bile Acids and Salts (Bile Acids)IBA
01/2016 - 01/2013
2Enzyme Precursors (Zymogens)IBA
01/2016 - 04/2012

Therapy/Procedure

6Therapeutics
01/2021 - 05/2004